Martin Luther University Halle-Wittenberg

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F.-J. Schmitt, A.S. Mehmood, C. Tüting, H.T. Phan, J. Reisdorf, F. Rieder, F.G. Golmohamadi, R. Verma, P.L. Kastritis, J. Laufer, "Effect of Molecular Dynamics and Internal Water Contact on the Photophysical Properties of Red pH-Sensitive Proteins", Biochemistry (2023)   

T. Kirchner, C. Villringer, J. Laufer, "Evaluation of ultrasound sensors for transcranial photoacoustic sensing and imaging", Photoacoustics,  33, 100556 (2023).   

J. Thümmler, R. Maragani, F.-J. Schmitt, G. Tang, S. Rahmanlou, J. Laufer, H. Lucas, K. Mäder, W. H. Binder, "Thermoresponsive Swelling of Photoacoustic Single-Chain Nanoparticles", Chemical Communications (2023).

W. Lebek, F. Heyroth, F. Syrowatka, C. Villringer, S. Goerlitz, J. Laufer "Evaluation of fabrication methods for Fabry-Perot polymer film ultrasound sensors", Proc. SPIE (2023)   

J. Sievers, C. Villringer, W. Lebek, T. Gilani, J. Laufer "Photoacoustic tomography using a Fabry-Perot sensor with homogeneous optical thickness and wide-field camera-based detection", Proc. SPIE (2023)   

T. Kirchner, C. Villringer, M. Gutke, J. Laufer "Plano-concave optical sensor for transcranial photoacoustic measurements", Proc. SPIE (2023)   

F. G. Golmohamadi, H. T. Phan, A. Mehmood, F.-J. Schmitt, J. Laufer "Difference imaging of red fluorescent proteins using pump-probe excitation", Proc. SPIE (2023)   

J. Reisdorf, J. Laufer, F.-J. Schmidt, "Depth and structure information in fluorescence molecular tomography obtained from time resolved spectroscopy," Proceedings of SPIE (2023)   


J. F. Thümmler, A. H. Roos, J. Krüger, D. Hinderberger, F.-J. Schmitt, G. Tang, F. G. Golmohamadi, J. Laufer, W. H. Binder, "Tuning the Internal Compartmentation of Single-Chain Nanoparticles as Fluorescent Contrast Agents" Macromolecular Rapid Communications (2022)   

T. Kirchner, "A micro-CT of a human skull" (2022) doi:10.48550/arXiv.2202.11519   


E. Baumann, U. Pohle, E. Zhang, T. Allen, C. Villringer, S. Pulwer, H. Gerhardt, J. Laufer, "A backward-mode optical-resolution photoacoustic microscope for 3D imaging using a planar Fabry-Pérot sensor" Photoacoustics 24 (2021).   

C. Villringer, P. Steglich, S. Pulwer, S. Schrader, J. Laufer, "Electro-optical properties of doped polymers with high transparency in the visible wavelength range" Optical Materials Express, 11(11), (2021).   


G. Pang, C. Haisch, J. Laufer, "Quenching of nonlinear photoacoustic signal generation in gold nanoparticles through coating" Nanoscale Advances, (2020).   

G. Pang, F. Poisson, J. Laufer, C. Haisch, E. Bossy, "Theoretical and Experimental Study of Photoacoustic Excitation of Silica-Coated Gold Nanospheres in Water" J. Phys. Chem. C 124, 1, 1088-1098 (2020). doi: 10.1021/acs.jpcc.9b09040   

J. Buchmann, B. Kaplan, S. Powell, S. Prohaska, J. Laufer, "Quantitative PA tomography of high resolution 3-D images: Experimental validation in a tissue phantom," Photoacoustics, 17 (2020).   


L.Theune, J. Buchmann, S. Wedepohl, M. Molina, J. Laufer, M. Calderón, "NIR- and thermo-responsive semi-interpenetrated polypyrrole nanogels for imaging guided combinational photothermal and chemotherapy," J. Contr. Rel. (2019). 10.1016/j.jconrel.2019.08.035   

J. Buchmann, B. Kaplan, S. Powell, S. Prohaska, J. Laufer, "Three-dimensional quantitative photoacoustic tomography using an adjoint radiance Monte Carlo model and gradient descent," J. Biomed. Opt. 24(6), 066001 (2019). doi:10.1117/1.JBO.24.6.066001   .


S. Schrof, G. Pang, J. Buchmann, J. Laufer „Exploiting Nonlinear Photoacoustic Signal Generation in Gold Nanospheres for Selective Detection in Serial 3D PA Tomography”, MDPI J. Imaging 4(12), 146 (2018). doi:10.3390/jimaging4120146   

J. Märk, H. Dortay, A. Wagener, E. Zhang, J. Buchmann, C. Grötzinger, T. Friedrich, J. Laufer „Dual-wavelength 3D photoacoustic imaging of mammalian cells using a photoswitchable phytochrome reporter protein”, Communications Physics 1(3) (2018). doi:10.1038/s42005-017-0003-2   

J. Laufer „Photoacoustic imaging: Principles and Application” in Quantification of Biophysical Parameters in Medical Imaging, ed. I. Sack, T. Schaeffter, Springer, doi:10.1007/978-3-319-65924-4    (2018).


J. Buchmann, J. Guggenheim, E. Zhang, C. Scharfenorth, B. Spannekrebs, C. Villringer, J. Laufer "Characterisation and modelling of Fabry-Perot ultrasound sensors with hard dielectric mirrors for photoacoustic imaging", Applied Optics 56(17), 5039-5046 (2017).

J. Brunker, J. Yao, J. Laufer, S. Bohndiek "A practical guide to photoacoustic imaging using genetically expressed reporters", Journal of Biomedical Optics (2017), in press.

J. Märk, A. Wagener, E. Zhang, J. Laufer “Photoacoustic pump-probe tomography of fluorophores in vivo using interleaved image acquisition for motion suppression”, Scientific Reports 7, 40496 (2017), doi: 10.1038/srep40496


G. Pang, J. Laufer, R. Niessner, C. Haisch “Photoacoustic signal generation in gold nanospheres in aqueous solution: signal generation enhancement and particle diameter effects” Journal of Physical Chemistry C 120(48), 27646-27656 (2016) doi: 10.1021/acs.jpcc.6b09374

J. Märk, F.-J. Schmitt, J. Laufer “Photoacoustic imaging of the excited state lifetime of fluorophores”, Journal of Optics 18(5), 054009 (2016), doi: 10.1088/2040-8978/18/5/054009


J. Märk, F.-J. Schmitt, C. Theiss, H. Dortay, T. Friedrich, J. Laufer "Photoacoustic imaging of fluorophores using pump-probe excitation", Biomedical Optics Express 6(7), 2522-2535 (2015). doi:  10.1364/BOE.6.002522

A. P. Jathoul, J. Laufer, O. Ogunlade, B. Treeby, B. Cox, E. Zhang, P. Johnson, A. R. Pizzey, B. Philip, T. Marafioti, M. F. Lythgoe, R. B. Pedley, M. A. Pule, and P. Beard, “Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter,” Nature Photonics, 2015, doi: 10.1038/nphoton.2015.22.


S. P. Johnson, O. Ogunlade, E. Zhang, J. Laufer, V. Rajkumar, R. B. Pedley, and P. Beard, “Photoacoustic tomography of vascular therapy in a preclinical mouse model of colorectal carcinoma,” in Proceedings of SPIE, 2014, vol. 8943, pp. 89431R–1 – 89431R–6.

J. Märk, K. Ruschke, H. Dortay, I. Schreiber, A. Sass, T. Qazi, M. Pumberger, and J. Laufer, “Development of tyrosinase-based reporter genes for preclinical photoacoustic imaging of mesenchymal stem cells,” in Proceedings of SPIE, 2014, vol. 8943, pp. 89433Z–1 – 89433Z–5.

J. Märk, C. Theiss, F.-J. Schmitt, and J. Laufer, “Photoacoustic imaging of a near-infrared fluorescent marker based on dual wavelength pump-probe excitation,” in Proceedings of SPIE, 2014, vol. 8943, pp. 894333–1 – 894333–7.


J. Laufer, A. Jathoul, M. Pule, and P. Beard, “Evaluation of genetically expressed absorbing proteins using photoacoustic spectroscopy,” in Proceedings of SPIE, 2013, vol. 8581, no. 85810X, pp. 1–6.

J. Laufer, A. Jathoul, M. Pule, and P. Beard, “In vitro characterization of genetically expressed absorbing proteins using photoacoustic spectroscopy,” Biomedical Optics Express, 2013, vol. 4, no. 11, pp. 2477–2490.

T. Oruganti, J. G. Laufer, and B. E. Treeby, “Vessel filtering of photoacoustic images,” in Proceedings of SPIE, 2013, vol. 8581, p. 85811W.


J. Laufer, A. Jathoul, P. Johnson, E. Zhang, M. Lythgoe, R. B. Pedley, M. Pule, and P. Beard, “In vivo photoacoustic imaging of tyrosinase expressing tumours in mice,” in Proceedings of SPIE, 2012, vol. 8223, pp. 82230M–1 – 82230M–5.

J. Laufer, F. Norris, J. Cleary, E. Zhang, B. Treeby, B. Cox, P. Johnson, P. Scambler, M. Lythgoe, and P. Beard, “In vivo photoacoustic imaging of mouse embryos,” Journal of Biomedical Optics, vol. 17, no. 6, p. 061220, 2012.

B. Cox, J. G. Laufer, S. R. Arridge, and P. C. Beard, “Quantitative spectroscopic photoacoustic imaging: a review,” Journal of Biomedical Optics, vol. 17, no. 6, p. 061202, 2012.